The Best Over-the-Counter Eye Drops for Dry Eye and Allergy Relief

Mild to Moderate Dry Eye Symptoms

Dry eye symptoms can range from occasional dryness to persistent irritation. Mild to moderate dry eye often presents as a gritty feeling, occasional burning or stinging, and intermittent blurry vision. Common triggers include dry environments, air conditioning, prolonged reading, or natural tear film instability. For these typical dry eye concerns, two OTC products offer reliable relief. 

Refresh Optive® GEL Drops

If your dryness goes beyond occasional discomfort, Refresh Optive® GEL Drops are a great choice. These gel-based drops can be used anytime—day or night—to form a soothing, protective layer over the eye. Their thicker consistency provides lasting hydration, easing moderate dry eye symptoms. Whether you’re battling dry indoor air or seasonal allergies, Refresh Optive® GEL Drops offer gentle, all-day comfort to keep your eyes feeling refreshed. 

Refresh Relieva® PF

When mild to moderate dryness flares during the day, Refresh Relieva® PF is a preservative-free option designed specifically for daytime use. These drops lock in moisture and help prevent further irritation, making them ideal for active individuals who want effective relief without the stinging sensation some drops cause. The preservative-free formula is gentle on sensitive eyes, providing sustained lubrication so you can stay comfortable without frequent rubbing or reaching for tissues. 

Screen-Induced Dry Eye Symptoms

With more time spent on computers, tablets, smartphones, and TVs, digital eye strain has become common. Staring at screens reduces your blink rate, causing tears to evaporate faster than they can be replenished. This often results in dry, tired eyes that burn, itch, or feel gritty—especially when you need your vision at its sharpest. 

Refresh Digital® PF

Refresh Digital® PF is formulated specifically to address the rapid dryness linked to extended screen use. These preservative-free drops are ideal for use during or right after long sessions on digital devices. They mimic natural tears to quickly restore moisture and provide relief without blurring your vision. The lightweight formula soothes irritation, helping you blink naturally and return to your screen with clear, comfortable eyes. 

Moderate to Intense Dry Eye Symptoms

If your eyes feel extremely dry, especially overnight, finding relief while you sleep is essential to avoid waking up irritated. Moderate to severe dry eye can be caused by chronic tear-film instability, certain medications, or environmental factors like low humidity. Without sufficient lubrication through the night, your eyes may become red, scratchy, and uncomfortable by morning. 

Refresh PM®

Refresh PM® is specially formulated for nighttime use, creating a protective, slow-release barrier that locks in moisture throughout the night. Its thick, ointment-like texture stays on the eye longer than standard drops, providing ongoing hydration and soothing relief for severe dry eye symptoms. Applying Refresh PM® before bed helps you wake with refreshed, comfortable eyes, reducing morning dryness and lessening the need for heavy daytime drops. 

Allergy Relief

Allergy season often brings itchy, watery eyes triggered by pollen, dust, or pet dander, which can make it difficult to focus or enjoy outdoor activities. Instead of constantly rubbing or rinsing, antihistamine eye drops work by blocking the chemicals that cause allergic reactions. 

Pataday®

Pataday® is a doctor-recommended, effective option for all-day relief from allergy symptoms. Many users apply it once in the morning and again in the evening to maintain comfort throughout the day. It blocks histamine, the primary cause of itching and tearing during allergies. With just one application providing up to 24 hours of protection, Pataday® helps keep your eyes calm and clear so you can enjoy your time outdoors without the constant urge to rub or wipe tears away. 

Choosing the Right OTC Eye Drops & When to Visit an Eye Doctor

Selecting the most effective eye drops starts with understanding the root cause of your symptoms. For occasional dryness, grittiness, or brief blurry vision, mild lubricants like Refresh Relieva® PF during the day or thicker options such as Refresh Optive® GEL for all-day relief can help restore comfort. If you notice dryness after extended use of computers or gaming devices, Refresh Digital® PF offers fast-acting relief designed for the reduced blink rate common with screen time. For severe dryness that worsens overnight, Refresh PM® provides a protective moisture shield to help you wake up refreshed. And if itchy, watery eyes are your main concern during allergy season, Pataday® delivers up to 24 hours of antihistamine relief with just one or two daily applications.

After choosing the product that suits your symptoms, it’s essential to follow the directions carefully. Always wash your hands before applying drops, avoid touching the bottle tip to your eyes or skin, and keep the cap tightly closed to prevent contamination. Be mindful of preservative warnings, especially if you have sensitive eyes, and discard bottles after their expiration date.

While OTC eye drops can address many mild to moderate eye issues, persistent or worsening symptoms should be evaluated by a professional. If you experience increasing redness, pain, discharge, light sensitivity, or vision changes that don’t improve after a week of proper use, schedule an appointment at Nationwide Vision. Our doctors can diagnose underlying conditions such as blepharitis, infections, or other serious eye problems and provide targeted treatments to restore your clear, comfortable vision.